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Protein stability tester
NanoTemper protein stability analyzer is a good assistant for antibody and vaccine formulations in biotechnology equipment. It is a natural DSF that d
Product details
NanoTemperProtein stability tester
A good assistant for antibody and vaccine formulations in bioengineering equipment
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Testing under natural conditions No need to add dyes or change the sample buffer. Can detect viscous samples. |
Obtain precise data High density data points mean high-quality data, while others We can obtain the details that were overlooked in the technology. |
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Consume fewer samples Sample size10 μl, sample concentration5 μg/mlIt can be detected.
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Free choice of flux Choose any number of samples for one experiment, which can be used1 One 48 One or any number of samples, or all of them can be selected Move the sample. |
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No need to prepare special samples The sample is directly drawn into the capillary without the need for a complex sample loading process |
Synchronizing measurements Synchronized to obtainTm、TonsetandTaggWaiting for multiple experimental results. |
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Detect more conditions Multiple parameters can be obtained in one test, allowing you to obtain results faster.
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Easy to regulate Synchronized to obtainTm、TonsetandTaggWaiting for multiple experimental results. conform to21 CFR Part 11Requirement, available at any time Where to use it. |
NanoTemperProtein stability tester
A good assistant for antibody and vaccine formulations in bioengineering equipment
When precision motters
PR NT.48be based onnanoDSFTechnology can detect protein thermal and chemical denaturation under natural conditions.
UnmarkednanoDSFTechnology can accurately detect changes in endogenous fluorescence during protein thermal and chemical denaturation processes.
nanoDSFThe use of high-quality capillaries brings many advantages: only a few microliters of sample are needed to complete experiments, and large samples can be detected
The concentration range of the product allows for simultaneous detection of samples under different conditions, obtaining multiple data simultaneously, and measuring viscous samples that are difficult to operate
Simply immerse one end of the capillary tube into the sample and place it inPR NT.48Sample stand, click start to get it quicklyTm, TonsetandTagg,
Cm,ΔGandΔΔGThe detection can also be completed in the same instrument.
When quality matters.
PR NT.48Excellent performance in detecting protein denaturation. Whether it is thermal or chemical denaturation research,PR NT.48All can be lightIdentify small changes that other technologies cannot detect. More importantly, the data quality will not be affected by the aggregates in the sample.Higher quality data enables you to make better decisions.
When confidence matters
A crucial point in research is to have confidence in what to do next. Boehringer Ingelheim（Boehringer Ingelheim)The formulationThe R&D department realized the importance of precise and high-quality thermal denaturation and aggregation data in screening candidate antibodies for long-term stable storage conditions,It is crucial for predicting antibody stability and long-term storage conditions.
No matter the size of the protein, whether it is an enzyme, antibody, antibody drug conjugate, or membrane protein,PR NT.48Can provide comprehensive analysis results.PR NT.48Especially skilled in buffer screening, formulation, and storage condition testing.
When guidance matters.
Finding a simple and easy-to-use scientific instrument is not an easy task.PR NT.48Used byPR.ThermControl、PR.ChemControlandPR.TimeControlThree types of software can guide researchers step by step to easily complete experimental settings.After the sample is loaded, the experimental setup can be completed immediately. From sample loading to experimental setup, every step goes through German engineeringTeacher's careful optimization in usability. During the experiment, you can edit and name the samples, and label them as different colors. experimentAfter completion, the results will be automatically displayed immediately. You can freely choose the desired results and share them with colleagues.
When options matter
NT.48 NT.Plex NT.Plex + NT.RA
Number of samples |
1 to48 individual (Single capillary tube) |
1 to24 individual (Capillary chip) |
1 to 1536 （1 to64 A capillary chip |
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Sample Volume |
10 μL |
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Sample concentration range |
0.005–250 mg/mL(standardIgG) |
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Single round testing time (thermal denaturation) Heating rate from1°C/minto 7°C/minadjustable |
18–75minute |
4 Hour to overnight (384 Sample) |
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Single round testing time (chemical denaturation) |
1 minute |
27 minutes(384Sample) |
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Temp Accuracy |
± 0.2 oC |
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Temperature range |
Heating rate:0.1°C/minto7°C/min Temperature control range:15°Cto95°C(Environmental temperature)25°C） |
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Fluorescence detection channel |
330 nmand350 nm |
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Instrument volume |
35 cm（long）x 51 cm（tall）x 52 cm（wide） |
110 cm（long）x 188 cm（tall） x 90 cm（wide） |
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Instrument weight |
30 kg |
200 kg |
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Optional upgrade |
Aggregation detection module |
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High temperature module 15°C-110°C(In)25°CAt ambient temperature) |
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