ParkNX12 Bio is a powerful three in one biological research tool that combines scanning ion conductivity microscopy(SICM)Atomic Force Microscopy(AFM)Inverted optical microscope(IOM)Integrated on the same platform.Park NX12-BioThe modular design allows you toSICMandAFMSwitch freely between them. In fusionSICM、AFMandIOMThe Biology-After the mechanical measurement function,Park NX12-Bio
This non-invasive liquid imaging tool has become an excellent choice for studying biomaterials under physiological conditions.
basic technique |
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scannerXY |
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scanner Flexible guided high propulsion scanner, flexible guided high propulsion scanner15Scanning range:30Optional(μm |
)Flexible guidance of closed-loop controlXY scanner100Scanning range:μm x 100μ |
m |
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Drive table |
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imageXYDrive table travel range: 50mm x 50mmZDrive table travel range: 25mmFocus on the travel range of the drive table: |
15mm Visual coaxial imaging of sample surface and cantilever840 view:μm x 630μ mcamera: |
5MPixel |
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Inverted optical microscopeObjective lens: until 100% fluorescence microscope |
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confocal microscope |
Standard imaging |
CHEMICALdielectric/ |
Piezoelectric performance Actual non-contact type contact AFM Lateral Friction Microscopic Technique(LFM ) Phase mode, tap mode batch |
AFM Chemical force microscope with functionalized probes Electrochemical microscope(EC-STMand EC-AFM) Scanning electrochemical cell microscope(SECCM ) Scanning electrochemical microscope(SECM |
) (EFM) efm Dynamic contact electron microscope(EFM-DC ) (PFM )Piezoelectric microscope high voltage |
PFM |
Force measurement |
Magnetic properties |
Thermal performance power-Distance(F-D )Spectral analysis power- volume imaging |
Calibration of elasticity coefficient using thermal noise method Mfm adjustable |
AFM Scanning thermal microscope(SThM |
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Electrical performance |
Electrical performance |
Mechanical properties
1) Can be imaged in liquid again2) Biological organization3D
imaging3) The most suitable temperature,PH
Value and humidity control to ensure biological activity4) Force versus distance(FD)
Spectroscopy can detect and characterize the mechanical properties of various biomaterials5) Accurate force to distance spectral control, coupled with leading low noiseZ
Axis detector1006) Force array imaging, compatible with all series of objectives, with high magnification up to
times
7) Integrating confocal microscopy and fluorescence microscopy
application
Application of Mechanics in Cell FixationOptical image of L929 cellsAFM (a)and
SICM (b)live(a)、(c)and4% PFAhandle(b)、(d) SICM
Cell surface imaging.
Related literature Seong-Oh Kim et al. “Correlating