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Mouse and Rat Sleep Deprivation Device
The Rat Sleep Deprivation System is an instrument that gently restricts sleep in animals without the need for training
Product details

The Rat Sleep Deprivation System is an instrument that gently restricts sleep in animals without the need for training. After the parameter settings are completed, sleep deprivation experiments can be conducted on rats or mice without human intervention. Can be used for sleep research, time difference research, and intermittent sleep model simulation.


The system has two models to choose from: Feedback and StandAlone


Stand Alone type



·Can be controlled by computer and host;

·Strike the stick at a set speed to disrupt animal sleep;

·It is possible to change direction through programming to reduce the adaptation of sleep deprived animals to their environment;

·The system can provide food, water, and a place for activities;

·There are two types of animal cages: rat cages and mouse cages;





Feedback type

·Sleep deprivation can be achieved through real-time monitoring of EEG/EMG electroencephalography signals using EEG/EMG system;

·The system can set the sleep state of animals, and when the real-time monitored EEG signals match or are similar to the pre-set sleep state, the system controls the rotation of the striking rod;

·Controlled by computer and controller touch screen;

·The system controls the striking rod based on real-time monitoring of EEG signals. The striking rod rotates at a set speed and can also be programmed to change direction to reduce the adaptation of sleep deprived animals to their environment;

·The system provides food, water, and a place to sleep, with animal cages divided into rat cages and mouse cages;








According to the needs, you can also choose a rotary bar sleep deprivation device or a sink type sleep deprivation box to conduct relevant experiments:



Product features of the rotary sleep deprivation device:

·It has four working modes: normally open, timed, intermittent, and forward/reverse;

·The rotating rod rotates gently and does not cause any mechanical damage to the animals;

·The timing mode can set the time for the interference rod to rotate;

·Intermittent mode can adjust the rotation time and stop time separately;

·In forward and reverse mode, the direction of operation of the interference rod can be set at regular intervals;

·The height of the rotating rod can be adjusted to reduce the impact of padding;

·Select rat and mouse type activity cages according to experimental requirements;

·We can also provide customized improvement services;




model: YAN-239



Main parameters:

·Four adjustable working modes;

·Timer mode time: 0-99h

·Intermittent mode time: 0-99min
·Forward and reverse mode time: 0-99min
·Adjustable range of rotating rod height: 10-30mm;

·Turning diameter 8mm;

·The length of the rotating rod is 36mm;
·Clear activity cage with a diameter of 40cm;

·The height of the rat cage is 17cm;

·The height of the mouse cage is 10cm;

·Customized improvement services are available;


You can choose a sink type sleep deprivation box according to your needs:



model: SY-M3100, Mice, 6 platforms

SY-M3040, mice, 40 platforms

SY-R3020, rats, 15 platforms

For more models, please call to inquire




The experiment of water tank sleep and fatigue deprivation in mice is currently underway



reference:

1. Cordeira, J., Kolluru, S.S., Rosenblatt, H., Kry, J., Strecker, R.E., McCarlet, R.W. (2017). Learning and memory are impaired in the object recognition task during metestrus/diestrus and after sleep deprivation. Behavioural Brain Research, 339, 124-129. doi: 10.1016/j.bbr.2017.11.033
2. Hines, D.J., Schmitt, L.I., Hines, R.M., Moss, S.J., & Haydon, P.G. (2013). Antidepressant effects of sleep deprivation require astrocyte-dependent adenosine mediated signaling. Translational Psychiatry, 3, e212. doi: 10.1038/tp.2012.136
3. Lee, D., Lee, S., & Sohn, D. (2016). MP86-19 effect of sleep deprivation on hormonal axis and erectile function. Journal of Urology, 195(4), e1113. doi:10.1016/j.juro.2016.02.2327
4. Lee, D.S., Sohn, D.W., Yoon, B.I., & Yoo, J.M. (2017). 383 effect of sleep deprivation on hormonal axis and erectile function. Journal of Sexual Medicine, 14(1), S113-S114. doi: 10.1016/j.jsxm.2016.11.264
5. Naidoo, N., Davis, J.G., Zhu, J., Yabumoto, M., Singletary, K., Brown, M., … & Baur, J.A. (2014). Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism. Aging Cell, 13(1), 131-141. doi: 10.1111/acel.12158
6. Schmidt, M.A. & Wisor, J.P. (2012). Interleukin 1 receptor contributes to methamphetamine- and sleep deprivation-induced hypersomnolence. Neuroscience Letters, 513(2), 209-213. doi: 10.1016/j.neulet.2012.02.040
7. Ward, C.P., Wooden, J.I., & Kieltyka, R. (2017). Effects of sleep deprivation on spatial learning and memory in juvenile and young adult rats. Psychology & Neuroscience, 10(1), 109-116. doi: 10.1037/pne0000075
8. Wooden, J., Pido, J., Mathews, H., Kieltyka, R., Montemayor, B., & Ward, C. (2014). Sleep deprivation impairs recall of social transmission of food preference in rats. Nature and Science of Sleep, 2014(6), 129-135. doi: 10.2147/NSS.S68611
9. Duncan, M. J., L. E. Guerriero, K. Kohler, L. E. Beechem, B. D. Gillis, F. Salisbury, C. Wessel, J. Wang, S. Sunderam, A. D. Bachstetter, B. F. O’Hara and M. P. Murphy, 2022. Chronic Fragmentation of the Daily Sleep-Wake Rhythm Increases Amyloid-beta Levels and Neuroinflammation in the 3xTg-AD Mouse Model of Alzheimer’s Disease. Neuroscience 481: 111-122.
10. Robinson-Junker, A., O’Hara, B., Durkes, A., Gaskill, B., 2019. Sleeping through anything: The effects of unpredictable disruptions on mouse sleep, healing, and affect. PloS one 14, e0210620.




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