Product Name: LCMS-8030 Liquid Chromatography Mass Spectrometry Analyzer

Product information:

Ultra fast analysis
Realize ultra fast MRM measurement with a maximum of 500 channels/second (minimum dwell time of 1msec, minimum delay time of 1msec), positive and negative polarity switching time of 15msec, and ultra fast scanning measurement with a maximum of 15000 uc. UFsweeper that can suppress crosstalk in high-speed analysis ® The collision chamber is combined with NexeraTM LC-30A to improve analysis throughput and enhance user analysis efficiency.

·Stability
Equipped with a high reliability ionization interface, stable and reliable data can be obtained during long-term measurements. Accurately capture sharp chromatographic peaks in ultra fast LC analysis to improve reproducibility. Minimizing crosstalk in the collision chamber ensures high quantitative accuracy.

·Easy to maintain
In daily work, the maintenance of the device is a heavy burden for users. Shimadzu listens to users' voices and provides them with a high degree of maintenance convenience.

·Operability
The LabSolutions LCMS new mass spectrometry workstation software for LCMS-8030 achieves smooth collection and analysis of LC/MS/MS data, pursues operability, and is equipped with optimized methods that can maximize device performance. The software with a unified interface with LC helps users become familiar with software operations faster.

Application example:

1. Utilizing NexeraTM LC-30A in combination with LCMS-8030 to achieve ultra fast mass spectrometry analysis. The following figure shows the simultaneous analysis of 226 pesticide components within 2 minutes, with a maximum peak width of less than 2 seconds.

Simultaneous analysis of 226 pesticides (sample concentration of 10ug/L)

2. The ultra fast mass spectrometry analysis of alprazolam showed an MRM ion pair of 309>281. The delay time is 1ms, and the reproducibility of the analysis is examined under different residence times.

The above figure shows the good reproducibility of ultra fast MRM analysis under different residence times

The following table shows the reproducibility% RSD results under different residence times

3 UFsweeper ® Technology can significantly reduce crosstalk caused by short dwell times. The following is the LCMS-8030 rapid analysis of verapamil (sample concentration of 1ug/mL), MRM ion pair 455.2>165.0, with a delay time and residence time of 3ms. Simultaneously monitor 470.0>165.0 ion pairs, with crosstalk less than 0.003%.

Equipped with UFsweeper ® LCMS-8030 technology achieves low crosstalk

Technical advantages of LCMS-8030 triple quadrupole liquid chromatography-mass spectrometer:

At present, the liquid chromatography part of liquid chromatography-mass spectrometry (LC-MS) has gradually evolved from HPLC (high-performance liquid chromatography) to UHPLC (ultra high performance liquid chromatography). Due to the fast peak extraction speed of UHPLC, the analysis speed of the mass spectrometry part of LC-MS must be very fast, otherwise the advantages of UHPLC's fast analysis cannot be fully utilized.

In response to this issue, Shimadzu Corporation has adopted UFsweeper in the Q2 collision chamber of the LCMS-8030 triple quadrupole ® Collision chamber technology (patent application pending) for rapid removal of product ions. In addition, during MRM detection, we also adopted Shimadzu's unique quadrupole RF voltage switching technology to shorten the delay time required for voltage setting between measurement channels, achieving ultra high speed MRM measurement of 500 channels per second. The LCMS-8030 adopts patented technologies such as UFscanning ultra fast scanning at a speed of up to 15000uc and UFswitching ultra fast positive and negative polarity switching at a speed of 15msec, enabling the LCMS-8030 to truly achieve high-throughput analysis without sacrificing signal strength.