Agilent AdvanceBio RP mAb liquid chromatography columnThe Agilent AdvanceBio RP mAb chromatographic column can optimize the performance of intact and reduced mAb analysis in the discovery, development, and QA/QC applications of monoclonal antibodies in biopharmaceuticals. The analysis of intact and reduced monoclonal antibodies is a key measurement for characterizing therapeutic proteins and understanding their efficacy and stability. Poor chromatographic separation may lead to rework and even affect the accuracy of characterization.Agilent AdvanceBio RP mAb liquid chromatography columnBased on Poroshell technology, with * pore size and bonding process design, higher separation and shorter running time can be achieved, providing accurate and reproducible results. This chromatographic column has different stationary phase chemical compositions - SB-C8, C4, and biphenyl.

characteristic

• Higher accuracy: The large pore size (450 Å) surface porous particle filler (3.5 µ m) is compatible with all liquid chromatographs and can improve mAb separation
• Fast analysis speed: Compared with chromatography columns filled with fully porous particle fillers of the same size, the analysis time is shorter
• Lower cost: The stable Poroshell packed bed and 2 µ m inlet sieve plate can prevent inlet blockage, thereby extending the service life of the column
• Flexible method development: with different stationary phase chemical compositions - SB-C8, C4, and biphenyl