Agilent 1290 Infinity LCInfinite excellent liquid chromatography system
Innovative new technologies bring stronger separation, higher sensitivity, and greater flexibility per unit time
With Agilent 1290 Infinity LC, you will no longer be limited by the choice of column size, packing type, mobile phase and stationary phase, flow rate, and pressure. No matter what optimal performance is required for chromatographic separation, the system can achieve it, thanks to its unique analytical capabilities and next-generation technology. Also included is the new ZORBAX RRHD 1.8 μ m chromatographic column - the only chromatographic column capable of operating at 1200 bar pressure.
The 1290 Infinity LC is also the first system that can transfer methods between any Agilent or non Agilent UHPLC and HPLC system. In short, it provides unlimited capabilities for users to tackle all challenges in LC and LC/MS analysis.

Infinite possibilities for excellent separation ability
Agilent's new 1290 Infinity binary pump brings you the best chromatographic performance, maximum compatibility, and flexibility. Active damping combined with the lowest delay volume - a patented technology in Agilent's new Jet Weaver mixer - provides ultra fast gradient response and excellent LC/UV and LC/MS performance.
The excellent separation capability of 1290 Infinity binary pump with infinite possibilities
The advanced technology of 1290 Infinity liquid chromatography is capable of meeting the challenges of UHPLC or HPLC, and its liquid delivery system opens the door to almost infinite improvements in separation and flux.
The characteristics are as follows:
• "Unlimited" functional range - flow rate up to 2 mL/min at 1200 bar pressure, 5 mL/min at 800 bar pressure, with unparalleled analysis speed and separation, and
Compatibility with methods developed on other platforms
• Minimum latency volume of 10 μ L - capable of ultra fast gradient separation compatible with LC/MS and LC/UV applications
Dual core microprocessor - controlled active damping - compensates for solvent properties, provides real-time flow optimization control, minimizes noise, and ensures maximum precision
Silicon carbide piston with excellent thermal behavior - prolongs the life of the sealing gasket and extends the normal operation time of the instrument
Integrated and efficient degassing - enables the pump to quickly empty and inject solvents
Infinite possibilities of super sensitivity
Featuring innovative optical path design, including Agilent's Max Light cartridge flow cells with microfluidic optical waveguide technology, the new 1290 Infinity diode array detector achieves new levels of UV sensitivity and baseline stability. For LC/MS, Agilent's jet stream ion focusing technology effectively improves the sensitivity of MS and MS/MS by improving the spatial focusing of electric spray droplets.
1290 Infinity diode array detector with infinite possibilities and super sensitivity
In order to ensure unparalleled detector sensitivity for both UHPLC and conventional HPLC, Agilent designed a maximum intensity card sleeve flow cell with microfluidic optical waveguide technology, which achieves an optical transmission rate of almost 100% without separation loss caused by cell diffusion effect, almost completely eliminating differential refractive index effect, and significantly reducing baseline drift.
• Lowest noise and highest linearity - using a 10 mm Agilent Max Light cartridge cell
• Ultra high sensitivity - using the unique 60 mm Agilent Max Light High Sensitivity cartridge cell
Due to the reduction of baseline drift, the integration processing of peaks is more reliable and stable
• Achieve multi wavelength and full spectrum detection at maximum acquisition rate (160Hz) - matching the speed of ultra fast liquid chromatography analysis
Programmable slit (1 to 8 nm) - provides optimal incident light, achieving rapid optimization of sensitivity, linearity, and spectral resolution
RFID barcodes for circulation pools and lights ensure data traceability and usage tracking
Simplified and user-friendly design - the card sleeve design makes the replacement of the circulation pool quick and easy

Infinite possibilities of excellent flexibility
Through the new Agilent quick switching valve in the 1290 Infinity column temperature chamber, a resource efficient solution for ultra-high throughput, multi method, and automatic method development has been achieved. A brand new component - the 1290 Infinity Flexible Cube, can use a fixed quantitative tube injection mode to achieve ultra fast cycle times or automatic needle recoil, minimizing cross contamination.
The excellent flexibility of the 1290 Infinity automatic sampler with infinite possibilities
The 1290 Infinity automatic sampler is based on advanced flow-through design, ensuring high-precision injection of both large and small volume samples without replacing the sample quantification tube.
Designed for the fastest sampling speed and minimum sample loss, this automatic sampler has the following features:
• Highest precision - injection range 0.1-40 μ L
• Minimum latency volume - suitable for the fastest gradient
Peltier temperature control range 4 to 40 ° C - suitable for heat sensitive samples
Overlapping injection - making the injection cycle shorter and more efficient
• Best anti cross contamination performance - achieved through inert sealing gasket and needle seat sealing gasket materials

1290 Infinity Column Temperature Box offers infinite possibilities for higher efficiency
The temperature range of the 1290 Infinity column incubator is from 10 ° C to 100 ° C below room temperature, providing greater flexibility in optimizing separation from both speed and selectivity. New Agilent quick replacement valve
This paves the way for developing solutions for ultra-high throughput, multi method, and automated methods.
The temperature stability parameter is ± 0.05 ° C, which improves the reproducibility of retention time
Peltier cooling/heating maximizes application flexibility - two independent temperature control zones ranging from 10 ° C below room temperature to 100 ° C
Low volume heat exchanger - minimizes peak diffusion
Spacious column box - can accommodate 3 30 cm chromatography columns or more short columns
Door opening sensor - improves safety and practicality
Achieve an analysis throughput of 2000 samples per day
The unique high-throughput configuration of 1290 Infinity liquid chromatography maximizes laboratory efficiency through high sample throughput. When using a chromatographic column for analysis, the regeneration pump
Clean and regenerate the second pillar. With this high-throughput configuration, the cycle time can be reduced by 50%.

Higher level control of 1290 Infinity liquid chromatograph
The Agilent Chemical Workstation, as the industry standard Agilent Instrumental Chromatography Data System (CDS), provides first-class instrument control for the new 1290 Infinity liquid chromatography
System. The new graphical user interface allows you to have a clear view of all important status parameters, browse all configured instruments, and directly enter all method settings.
Chemical workstations help improve the efficiency of all commonly used separation techniques, including Agilent gas chromatography, liquid chromatography, LC/MS, CE and CE/MS, as well as many others
Three party detector. This is a durable and upgradable chromatographic data system suitable for various applications in all industries, including early product development to quality control.
Extensive customization features, including authentication, provide you with flexibility to support different workflows.