• Product Name: 17020 Bronchospasmodic Sensor
• Order number: tlyon000398
• Brand Name: Ugo Italy

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17020- Bronchospasmodic Sensor

The bronchospasm sensor is designed for bronchospasm testing in lung research, especially asthma research. This provides researchers with a new method for evaluating drug-induced spasticity effects without the need for respiratory dynamics. The main body of the instrument is an air flow meter equipped with an adjustable pressure threshold inlet valve. It can be connected to 17400 data loggers or other data recording devices, as well as icon loggers. The entire device is a closed space made of organic glass, with its own power supply and control system.

The 17020 bronchospasm sensor is an effective tool for screening drugs that induce opposite effects, such as bronchodilators, histamine, and bradykinin. It is worth noting that bronchospasm testing is generally conducted using guinea pigs

characteristic:

A simple and reliable method to evaluate airflow resistance
Quickly evaluate the effects of bronchodilators (by simply connecting to an animal ventilator and data acquisition system or chart recorder)
The new signal measurement accuracy can reach 0.1ml and can be used with ventilators and data recording equipment

Specifications:

Net weight: 2.7Kg
Gross weight: 5.5Kg
Packaging: 40x39x30cm

enclosure:

7021 7022	Airflow head sprayer
7024	Anesthetic box
7025	Rodent ventilator

reference:

Regarding Methods

- H.Konzett & R. Roessler: Arch. Exp. Path. Pharmakol.: 195, 171, 1940

Related literature related to 7020

K. Ogino et alia: “PM2.5-Induced Airway Inflammation And Hyperresponsiveness In Nc/Nga Mice” Environmental Toxicol. 10.1002/tox.22303, June 2016

- I. Murakami et alia: “Rebamipide Suppresses Mite-Induced Asthmatic Responses in NC/Nga

Mice” Am. J. Physiol., Lung Cellular and Molecular Physiology 309(8): L872-878, 2015

- K. Ogino et alia: “Anti-inflammatory Effect of Arginase Inhibitor and Corticosteroid on Airway Allergic Reactions in a Dermatophogoides farinae-induced NC/Nga Mouse Model” Inflammation 36 (1): 141-151, 2013

- S.J.S. Flora et alia: “Interactive effect of arsenic and fluoride on cardio-respiratory disorders in male rats: possible role of reactive oxygen species” BioMetals 24 (4): 615-628, 2011

- N.R.F. Nascimento et alia: “1,8-Cineole induces relaxation in rat and guinea-pig airway smooth muscle” J. Pharmacy and Pharmacol. 61 (3): 361-366, 2009

- A. Floch et alia: “Characterization of NK1 and NK2 tachykinin receptors in guinea-pig and rat bronchopulmonary and vascular systems” Br. J. Pharmacol. 111 (3): 759-768, 1994

- W.A.K. Lau et alia: “Methoxyphenamine inhibits basal and histamine-induced nasal congestion in anaesthetized rats” Br. J. Pharmacol. 101 (2): 394-398, 1990

- C. Broquet et alia: “Aminoacylates and Aminocarbamates of 2-substituted 4-hydroxymethyl 1,3-dioxolans as Ammonium Salts. A new Series of PAF Antagonists“ Eur. J. Med. Chem.: 25: 235-240, 1990.